Novel uses for ascorbyl-phosphoryl-cholesterol in topical...

Details Novel uses for ascorbyl-phosphoryl-cholesterol in topical... Novel uses for ascorbyl-phosphoryl-cholesterol in topical...

A - Human Necessities

61

K

A61K 8/63 (2006.01) A61K 8/67 (2006.01) A61K 31/665 (2006.01)

Patent

CA 2244535

Novel uses of 3'-(L-ascorbyl-2-o-phosphoryl)-cholesterol, 3'-(L-ascorbyl-3-o-phosphoryl)-cholesterol, structural or functional isomers thereof and salts thereof (referred to collectively as "APC compounds") are disclosed. Such novel uses include a method of reducing epidermal synthesis of abnormal elastin, especially epidermal synthesis of abnormal elastin that results from exposure to UV radiation. Also disclosed is a novel method of stimulating keratinocyte formation of triglycerides. In addition, a novel method of achieving antioxidant activity, both in the skin and also in topical compositions, is disclosed.

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