A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/00 (2006.01) A61K 33/14 (2006.01) G01N 33/49 (2006.01) G01N 33/84 (2006.01)
Patent
CA 2244454
The invention concerns a pharmaceutical composition of a sterile, injectable physiologically acceptable solution containing nitric oxide (NO). The invention also concerns a process for preparing this composition and a process for detecting physiologically present NO. With the NO solution according to the invention, NO in high doses can trigger locally in vessels (for example coronary vessels) specific local biological effects such as relaxation of the smooth vascular musculature, inhibition of the adhesion of thrombocytes, etc., without producing systemic side-effects, such as for example a critical drop in blood pressure, in spite of the high doses. The detection process according to the invention enables the presence of an endothelial dysfunction to be established from the whole blood of humans and other mammals.
L'invention concerne une composition pharmaceutique d'une solution stérile injectable, physiologiquement acceptable, qui contient du monoxyde d'azote (NO). L'invention concerne également un procédé permettant de préparer ladite composition et un procédé de détection du NO physiologiquement présent. La solution de NO obtenue selon l'invention permet au NO présent localement en doses élevées, de déclencher dans les vaisseaux (par ex. vaisseau coronaire) des effets biologiques ciblés localement, tels que la relaxation des muscles vasculaires lisses, l'inhibition de l'adhérence de thrombocytes, etc., sans entraîner pour autant d'effets secondaires systémiques tels que par ex. une baisse de tension critique. Ce procédé de détection permet de mettre en évidence un dysfonctionnement endothélial sur la base d'un échantillon de sang entier d'humains/mammifères.
Kelm Malte
Robic
Schwarz Pharma Ag
LandOfFree
Use of nitric monoxide for preparing medication for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of nitric monoxide for preparing medication for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of nitric monoxide for preparing medication for... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1488673