Pharmaceutical compositions and dosage forms for buccal and...

Details Pharmaceutical compositions and dosage forms for buccal and... Pharmaceutical compositions and dosage forms for buccal and...

A - Human Necessities

61

K

A61K 31/433 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 31/4168 (2006.01) A61K 31/4178 (2006.01)

Patent

CA 2505861

Sublingual and buccal administration of the muscle spasm suppressor tizanidine increase its bioavailability by avoiding first-pass metabolism in the liver and reduce the inter-patient variation in bioavailability.

L'administration par voie buccale et sublinguale d'un antispasmodique musculaire, la tizanidine, permet d'augmenter la biodisponibilité de cet antispasmodique en évitant le métabolisme de premier passage dans le foie, et de réduire les variations de la biodisponibilité entre les patients.

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