Apparatus and method for reconstituting a pharmaceutical and...

A - Human Necessities – 61 – M

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Details

A61M 35/00 (2006.01) A61F 9/00 (2006.01) A61J 1/06 (2006.01) A61J 1/14 (2006.01) A61J 1/20 (2006.01) A61K 31/407 (2006.01) A61P 27/02 (2006.01) B65D 85/00 (2006.01)

Patent

CA 2659314

An apparatus for preparing a pharmaceutical for transient application includes a tray having a sealed compartment, a vial of an ophthalmic formulation of mitomycin-C, a diluent carrier containing sterilized water, and a syringe that are all contained together in a single package. The component parts of the apparatus are used together to reconstitute the contents of the vial with the water in the diluent carrier, and then draw the reconstituted drug into the sealed compartment of the tray by a suction force produced by the syringe. In the tray compartment, the reconstituted drug is absorbed in an absorbent pad. The tray is opened to remove the pad and the absorbed drug from the tray compartment for use of the pad in transient application of the drug.

L'invention concerne un dispositif de préparation d'un produit pharmaceutique en vue d'une application transitoire, qui comprend un plateau à compartiment étanche, un flacon contenant une formulation ophtalmique à base de mitomycine-C, un support de dilution contenant de l'eau stérilisée et une seringue, le tout étant contenu dans un seul bloc. L'ensemble des parties constitutives du dispositif sont utilisées pour reconstituer le contenu du flacon avec de l'eau dans le support de dilution, le médicament ainsi reconstitué étant attiré dans le compartiment étanche du plateau sous l'effet de la force d'aspiration produite par la seringue. Dans le compartiment du plateau, le médicament reconstitué est absorbé par une éponge absorbante. Le plateau est ouvert pour extraire l'éponge ainsi que le médicament absorbé du compartiment du plateau. L'éponge est alors utilisée dans une application transitoire du médicament.

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