Cyclodextrin inclusion complexes and methods of preparing same

C - Chemistry – Metallurgy – 07 – G

Patent

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C07G 99/00 (2009.01) A61K 31/70 (2006.01) C07H 1/00 (2006.01)

Patent

CA 2610471

Cyclodextrin inclusion complexes and methods for preparing and using the cyclodextrin inclusion complexes. A method for preparing a cyclodextrin inclusion complex can include dry blending cyclodextrin, an emulsifier and a thickener to form a dry blend, and mixing a solvent and a guest with the dry blend to form a mixture comprising a cyclodextrin inclusion complex. In some embodiments, the mixture can be dried to form a dry powder or emulsified to form an emulsion. The dry powder or the emulsion can be used in a variety of applications (e.g., beverages, food products, chewing gums, dentifrices, candy, flavorings, fragrances, pharmaceuticals, nutraceuticals, cosmetics, agricultural products, photographic emulsions, waste stream systems, and combinations thereof).

La présente invention décrit des complexes d'inclusion de cyclodextrine ainsi que des méthodes de préparation et d'utilisation desdits complexes d~inclusion de cyclodextrine. Une méthode de préparation d'un complexe d'inclusion de cyclodextrine peut inclure le mélange à sec d'une cyclodextrine, d'un émulsifiant et d'un épaississant pour former une formule sèche, et le mélange d'un solvant et d'un adjuvant avec la formule sèche pour obtenir un mélange comprenant un complexe d'inclusion de cyclodextrine. Dans certains modes d'application, ledit mélange peut être séché pour former une poudre sèche, ou émulsifié pour former une émulsion. La poudre sèche ou l'émulsion peuvent être employées dans une diversité d'applications (par exemple boissons, produits alimentaires, gommes à mâcher, dentifrices, sucreries, arômes, fragrances, produits pharmaceutiques, produits nutraceutiques, produits cosmétiques, produits agricoles, émulsions photographiques, systèmes d'évacuation et combinaisons de ces applications).

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