Novel antiandrogenic agents and related pharmaceutical...

Details Novel antiandrogenic agents and related pharmaceutical... Novel antiandrogenic agents and related pharmaceutical...

C - Chemistry, Metallurgy

07

J

C07J 1/00 (2006.01) A61K 31/56 (2006.01) C07J 9/00 (2006.01) C07J 21/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 2180548

Novel antiandrogenic agents are provided. An exemplary group of compounds has the structural formula (I), wherein R1 through R10, a and b are as defined herein. Pharmaceutical compositions and methods for using the compounds of formula (I) to treat androgen-related clinical conditions are provided, as are methods and compositions for using the compounds as contraceptive agents.

Nouveaux agents antiandrogènes dont l'un des groupes types présente la formule (I) où R?1¿ à R?10¿, a et b sont définis ici. Préparations pharmaceutiques à base des composés de formule (I) et leur mode d'utilisation en vue du traitement d'états cliniques liés aux androgènes et méthodes et préparations utilisant ces composés comme agents contraceptifs.

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