Therapeutic agent for anca-related vasculitis

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/202 (2006.01) A61K 31/232 (2006.01) A61K 31/616 (2006.01) A61P 11/00 (2006.01) A61P 13/12 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2734870

Disclosed is an agent for preventing/treating ANCA-related vasculitis and/or preventing the recurrence of ANCA-related vasculitis. Also disclosed is a therapeutic method using the agent. Specifically disclosed is a pharmaceutical composition comprising at least one member selected from the group consisting of eicosapentaenoic acid, a pharmaceutically acceptable thereof and an ester thereof as an active ingredient. The pharmaceutical composition is useful for the prevention of recurrence of ANCA-related vasculitis, the treatment of chronic ANCA-related vasculitis, and the prevention and treatment of rapidly progressive glomerulonephritis (RPGN).

L'invention porte sur un agent destiné à prévenir/traiter une angéite liée à ANCA et/ou prévenir la rechute d'une angéite liée à ANCA. L'invention porte également sur un procédé thérapeutique utilisant l'agent. L'invention porte spécifiquement sur une composition pharmaceutique comprenant au moins un élément choisi dans le groupe constitué par l'acide éicosapentaénoïque, un sel pharmaceutiquement acceptable de celui-ci et un ester de celui-ci en tant qu'ingrédient actif. La composition pharmaceutique est utile pour la prévention de la rechute d'une angéite liée à ANCA, le traitement d'une angéite chronique liée à ANACA et la prévention et le traitement d'une glomérulonéphrite à progression rapide (RPGN).

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