Carrier for medicaments for obtaining oral bioavailability

A - Human Necessities – 61 – K

Patent

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A61K 47/48 (2006.01)

Patent

CA 2574124

The invention relates to a protein complex consisting of at least one hemagglutinin from at least one of the Clostridium botulinum types A, B, C, D, E, F or G and a polypeptide Hc conjugate, whereby the polypeptide Hc conjugate is comprised of a selected polypeptide bound to the heavy chain or the N- terminal fragment of botulinum toxin.

La présente invention concerne un complexe protéique composé d'au moins une hémagglutinine d'au moins un type parmi les types de Clostridium botulinum A, B, C, D, E, F ou G et d'un conjugué chaîne lourde-polypeptide, ledit conjugué chaîne lourde-polypeptide étant composé d'un polypeptide sélectionné, lié à la chaîne lourde ou son fragment N-terminal de la toxine botulique.

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