Novel human endogenous retorviral erv3 variant and uses...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12N 15/13 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) C07K 14/15 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2745849

The present invention relates to polynucleotide and polypeptide sequences of a novel human endogenous retroviral ERV3 variant which is differentially expressed in ovarian cancer cells when compared to normal cells. The present invention more particularly relates to the use of these polynucleotide and polypeptide in the diagnosis, prognosis or treatment of cancer and in the detection of cancer cells.

La présente invention concerne des séquences polynucléotidique et polypeptidique dun nouveau variant rétroviral endogène humain dERV3 qui est exprimé de manière différentielle dans des cellules de cancer des ovaires par rapport à des cellules normales. La présente invention concerne plus particulièrement lutilisation de ces polynucléotide et polypeptide dans le diagnostic, le pronostic ou le traitement du cancer et dans la détection de cellules cancéreuses.

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