Oral drug delivery compositions and methods

Details Oral drug delivery compositions and methods Oral drug delivery compositions and methods

A - Human Necessities

61

K

A61K 47/20 (2006.01) A61K 9/16 (2006.01) A61K 31/16 (2006.01) A61K 31/352 (2006.01) A61K 31/727 (2006.01) A61K 38/21 (2006.01) A61K 38/23 (2006.01) A61K 38/25 (2006.01) A61K 38/27 (2006.01) A61K 47/16 (2006.01) C07C 229/42 (2006.01) C07C 233/55 (2006.01) C07C 233/61 (2006.01) C07C 233/63 (2006.01) C07C 233/87 (2006.01) C07C 235/38 (2006.01) C07C 235/64 (2006.01) C07C 235/84 (2006.01) C07C 237/22 (2006.01)

Patent

CA 2160693

The present invention relates to an oral drug delivery system, and in particular to modified amino acids and modified amino acid derivatives for use as a delivery system of sensitive agents such as bioactive peptides. The modified amino acids and derivatives can form non-covalent mixtures with active biological agents and in an alternate embodiment can releasably carry active agents. Modified amino acids can also form drug containing microspheres. These mixtures are suitable for oral administration of biologically active agents to animals. Methods for the preparation of such amino acids are also disclosed.

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