Sustained-release preparation of basic medical agent...

A - Human Necessities – 61 – K

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167/155, 167/166

A61K 47/38 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 9/62 (2006.01) A61K 31/425 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2028633

ABSTRACT OF THE DISCLOSURE A preparation obtained by coating granules containing both a basic medical agent hydrochloride (e.g. allotinolol hydrochloride) and a polyanion the particles of which are present in the form of a discontinuous layer, with a film containing a slightly water-soluble substance, can release said agent at a controlled rate without influenced by the physiological factors of the gastrointestinal tract of a patient when orally administered.

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