Polypeptides

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C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) C07K 14/195 (2006.01) C07K 14/245 (2006.01) C07K 14/315 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 9/10 (2006.01) C12N 9/14 (2006.01) C12N 15/55 (2006.01) C12N 15/56 (2006.01) C12N 15/57 (2006.01) C12N 15/70 (2006.01) C12N 15/71 (2006.01) C12N 15/74 (2006.01) C12N 15/75 (2006.01) C12P 21/02 (2006.01) C12Q 1/34 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2150532

The present invention relates to variants of Penicillin Binding Proteins (PBP), which proteins are involved in bacterial peptidoglycan biosynthesis. Disclosed are also DNA molecules coding for the said PBP variants, as well as vectors and cells harbouring such DNA molecules. The invention is also related to processes for assaying and designing therapeutically useful compounds which have high affinity to PBP, which processes utilize the said PBP variants.

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