C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12N 15/62 (2006.01) C12N 15/85 (2006.01) G01N 33/50 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2397207
The present invention is directed to novel polypeptides having sequence similarity to Stra6, a murine retinoic acid responsive protein, and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
La présente invention concerne de nouveaux polypeptides présentant une séquence similaire à celle de Stra6, une protéine murine sensible à l'acide rétinoïque, et des molécules d'acide nucléique codant ces polypeptides. L'invention concerne également des vecteurs et des cellules hôtes renfermant ces séquences d'acide nucléique, des molécules de polypeptides chimériques renfermant les polypeptides de la présente invention liées par fusion à des séquences polypeptidiques hétérologues, des anticorps qui se fixent sur les polypeptides de la présente invention et des méthodes destinées à la production des polypeptides de la présente invention.
Pennica Diane
Smith Victoria
Wood William I.
Genentech Inc.
Smart & Biggar
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