Dna-constructs of blood clotting factors and p-selectin

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) A61P 7/00 (2006.01) C07K 14/705 (2006.01) C07K 19/00 (2006.01) C12N 9/64 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2291453

A DNA construct is disclosed which encodes a fusion protein comprising an amino acid sequence of a blood clotting factor like Factor IX and an amino acid sequence of the cytoplasmic domain of P-Selectin. Such construct may be used for the somatic gene therapy of patients suffering from a defiency of a blood coagulation factor.

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