Iontophoretic transdermal system for the administration of...

A - Human Necessities – 61 – N

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A61N 1/30 (2006.01)

Patent

CA 2217014

A transdermal system (1) for administrating at least two substances through the skin by means of an electric current has a reservoir comprising a storage layer (2) for the substances to be administrated and a transfer device which may take the form of a separation layer (3), which is in contact with both the reservoir and a patient's skin (5) during release. The transdermal system also has electrodes (4) which generate a current transporting the substances from the reservoir into the skin (5). There are means in the transdermal system (1) for spatially separating the substances, making it possible to administrate the substances in succession.

L'invention concerne un système transdermique (1) qui permet d'administrer au moins deux substances à travers la peau à l'aide d'un courant électrique. Ce système comporte un réservoir comprenant une couche de stockage (2) pour les substances à administrer, ainsi qu'un dispositif de transfert pouvant se présenter sous forme de couche de séparation (3). Pendant le processus d'administration, ce dispositif de transfert est aussi bien en contact avec le réservoir qu'avec la peau du patient. Ce système transdermique comporte en outre des électrodes (4) qui produisent un courant servant à transporter les substances du réservoir à l'intérieur de la peau (5). Il est prévu dans ce système transdermique (1) des éléments de séparation spatiale des substances qui permettent de procéder à un mode d'administration séquentiel des substances.

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