Preparations of non-steroidal analgesics

Details Preparations of non-steroidal analgesics Preparations of non-steroidal analgesics

A - Human Necessities

61

K

A61K 31/19 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2243522

The invention concerns preparation of non-steroidal analgesics with antipyretic and antiphlogistic effect, obtained through extrusion and moulding of a melt containing in addition one or more substances in a mixture of a) 40 to 99.5 wt% of a homopolymer of N--vinylpyrrolidone with a K value according to Fikentscher of 30; b) 0.25 to 59.75 wt% of a water-soluble copolymer of N-vinylpyrr olidone; and c) 0.25 to 10 wt% of one or more physiologically ac ceptable sodium- or potassium salts, whee the quantities refer to the total of the components a), b) and c).

L'invention concerne des analgésiques non stéroïdiens à action antipyrétique et antiphlogistique, que l'on produit en extrudant et en moulant une masse fondue contenant, outre un ou plusieurs principes actifs, un mélange de: a) 40 à 99,5 % en poids d'un homopolymère de N-vinylpyrrolidone présentant une valeur K d'après Fikentscher de 30; b) 0,25 à 59,75 % en poids d'un copolymère hydrosoluble de N-vinylpyrrolidone; et c) 0,25 à 10 % en poids d'un ou plusieurs sels physiologiquement acceptables de sodium ou de potassium, ces quantités étant données par rapport à la somme des composants a), b) et c).

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