Live attenuated salmonella strains for producing vaccines

Details Live attenuated salmonella strains for producing vaccines Live attenuated salmonella strains for producing vaccines

C - Chemistry, Metallurgy

12

N

C12N 1/36 (2006.01) A61K 39/112 (2006.01)

Patent

CA 2461145

Disclosed herein methods for producing live attenuated Salmonella typhi, Salmonella paratyphi A and B and other Salmonella mutants which can be used in vaccines to prevent diseases caused by Salmonella infection. These mutants can also be used to prevent or treat diseases caused by other bacterial strains, by viral and parasitic pathogens and by tumor cells.

L'invention concerne des méthodes de production de mutants vivants atténués de Salmonella typhi, de Salmonella paratyphi A et <I>B </I>et d'autres Salmonella, pouvant être utilisés dans des vaccins pour prévenir les maladies causées par une infection à Salmonella. Ces mutants peuvent également être utilisés dans la prévention ou le traitement de maladies causées par d'autres souches bactériennes, par des agents pathogènes viraux et parasites et par des cellules tumorales.

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