C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/24 (2006.01) C07K 1/00 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) C12N 15/02 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2343655
The present invention relates to a novel IL17RLP protein which is a member of the interleukin(IL)-17 receptor family. In particular, isolated nucleic acid molecules are provided encoding the human IL17RLP protein. IL17RLP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of IL17RLP activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.
La présente invention a trait à une nouvelle protéine IL17RLP qui fait partie de la famille des récepteurs d'interleukine (IL)-17. L'invention concerne notamment des molécules d'acides nucléiques isolées qui codent pour la protéine IL17RLP humaine. L'invention concerne également des polypeptides d'IL17RLP, des vecteurs, des cellules hôtes et des procédés de recombinaison permettant de produire ceux-ci. L'invention concerne en outre des procédés de criblage permettant d'identifier des agonistes et des antagonistes de l'activité d'IL17RLP. L'invention concerne aussi des méthodes diagnostiques permettant de détecter des troubles liés au système immunitaire, et des méthodes thérapeutiques servant à traiter des troubles liés au système immunitaire.
Ruben Steven M.
Shi Yanggu
Human Genome Sciences Inc.
Mbm Intellectual Property Law Llp
LandOfFree
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