Synthetic dna derived recombinant hiv antigens

Details Synthetic dna derived recombinant hiv antigens Synthetic dna derived recombinant hiv antigens

Category

C - Chemistry, Metallurgy

Subcategory

12

Subsubcategory

N

CPC

530/13, 167/44,

IPC codes

C12N 15/49 (2006.01) C07K 14/155 (2006.01) C07K 14/16 (2006.01) C07K 19/00 (2006.01) G01N 33/569 (2006.01)

Type

Patent

Patent number

CA 2003383

Description

ABSTRACT The present invention provides a method of synthesizing genes encoding unique HIV-1 and HIV-2 envelope proteins and their fragments, thereby allowing overexpression of these proteins in E. coli. The HIV envelope proteins and their fragments have been expressed at high levels as individual proteins or in fusion with other proteins. The HIV envelope proteins thus expressed in E. coli can be effectively used for the detection of exposure to HIV as well as the discrimination of HIV-1 and HIV 2.

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