Single nucleotide polymorphisms and combinations thereof...

Details Single nucleotide polymorphisms and combinations thereof... Single nucleotide polymorphisms and combinations thereof...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12M 1/34 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2468312

Single nucleotide polymorphisms (SNPs) and combinations of SNPs that allow an inference as to whether a cancer patient is likely to respond or not respond to paclitaxel (Taxol®) are provided. Also provided are methods of determining a whether a cancer patient should be treated with paclitaxel.

La présente invention concerne des polymorphismes nucléotidiques simples (SNP) et des combinaisons de SNP qui permettent de supposer qu'un patient atteint de cancer sera sensible ou ne sera pas sensible au paclitaxel (Taxol3). Cette invention concerne aussi des techniques permettant de déterminer si un patient atteint de cancer doit être traité au paclitaxel.

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