Substituted deuterium enriched thiophenes for the treatment...

Details Substituted deuterium enriched thiophenes for the treatment... Substituted deuterium enriched thiophenes for the treatment...

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/42 (2006.01) A61P 9/12 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2683857

Disclosed herein are substituted pyrimidine-based endothelin modulators of Formula I, processes of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.

L'invention concerne des modulateurs de l'endothéline substitués à base de pyrimidine représentés par la formule I, des procédés de préparation de ces composés, des compositions pharmaceutiques renfermant ceux-ci et des procédés d'utilisation de ceux-ci.

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