Single nucleotide polymorphisms diagnostic for schizophrenia

Details Single nucleotide polymorphisms diagnostic for schizophrenia Single nucleotide polymorphisms diagnostic for schizophrenia

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61P 25/18 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2441353

The invention provides nucleic acid segments of the human G protein coupled receptor Con-202 gene including polymorphic sites. Allele specific primers and probes hybridizing to regions flanking these sites are also provided. The invention also provides methods for determining the genetic risk of developing schizophrenia or diagnosing schizophrenia.

L'invention porte sur des segments d'acide nucléique du gène humain Con-202 du récepteur couplé à la protéine G comprenant des sites polymorphiques. L'invention porte également sur des amorces spécifiques d'allèle et sur des sondes s'hybridant aux régions bordant ces sites, ainsi que sur des procédés de détermination du risque génétique à développer ou diagnostiquer la schizophrénie.

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