Substituted pyrrolo-pyrazole derivatives active as kinase...

Details Substituted pyrrolo-pyrazole derivatives active as kinase... Substituted pyrrolo-pyrazole derivatives active as kinase...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/41 (2006.01) A61K 31/496 (2006.01) A61K 31/5355 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2631907

Substituted pyrrolo-pyrazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and 5 pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with dysregulated protein kinase activity, like cancer.

L'invention concerne des dérivés de pyrrolo-pyrazole substitués de formule (I) et des sels de ceux-ci acceptables d'un point de vue pharmaceutique, tels que définis dans le descriptif, leurs procédés de préparation et des compositions pharmaceutiques les comprenant. Les composés de cette invention peuvent être utiles en thérapie dans le traitement des maladies associées à l'activité dérégulée de la protéine kinase, telles que le cancer.

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