Streptococcal c5a peptidase vaccine

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/09 (2006.01) A61K 38/48 (2006.01) A61K 39/385 (2006.01) C12N 9/52 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2243755

Novel vaccines for use against .beta.-hemolytic Streptococcus colonization or infection are disclosed. The vaccines contain an immunagenic amount of streptococcal C5a peptidase, or a fragment or mutant thereof. Also disclosed is a method of protecting a susceptible mammal against .beta.-hemolytic Streptococcus colonization or infection by administering such a vaccine.

La présente invention concerne des vaccins contre la colonisation ou l'infection par Streptococcus beta -hémolytique. Le vaccin contient une quantité immunogène de peptidase C5a du streptocoque, ou bien l'un de ses fragments ou l'un de ses mutants. L'invention concerne également un procédé de protection d'un mammifère sensible contre la colonisation ou l'infection par Streptococcus beta -hémolytique, et ce, par administration d'un tel vaccin.

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