C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 275/30 (2006.01) A61K 31/17 (2006.01) A61P 11/06 (2006.01) C07C 227/08 (2006.01) C07C 227/16 (2006.01) C07C 227/18 (2006.01) C07C 229/58 (2006.01) C07C 273/18 (2006.01) C07C 275/42 (2006.01) C07C 311/21 (2006.01)
Patent
CA 2680139
There is provided compounds of formula (I), wherein Rx, Ry, X1, X2, L1, L2, Y1 and Y2 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
L'invention concerne des composés représentés par la formule (I), dans laquelle Rx, Ry, X1, X2, L1, L2, Y1 et Y2 ont la signification donnée dans la description, et des sels pharmaceutiquement acceptables de ceux-ci. Lesdits composés sont utiles dans le traitement de maladies dans lesquelles l'inhibition de l'activité de la leucotriène C4 synthase est souhaitée et/ou requise et, en particulier, dans le traitement d'un trouble respiratoire et/ou d'une inflammation.
Nilsson Peter
Pelcman Benjamin
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Biolipox Ab
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