C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/02 (2006.01)
Patent
CA 2689056
The present invention describes novel 4-quinolinones corresponding to formula (I) and quinoline derivatives thereof as formula (II), process of preparation thereof, pharmaceutical formulations comprising said 4-quinolinones and pharmaceutical application thereof for diseases related to disorders of white blood cells, such as inflammatory and autoimmune diseases, including rheumatism, as well as the use as anti-coagulant, antivenin, analgesic and for antithrombotic purposes.
La présente invention porte sur de nouvelles 4-quinolinones correspondant à la formule (I) et des dérivés de quinoléine de celles-ci correspondant à la formule (II), sur un procédé permettant de les préparer, sur des formulations pharmaceutiques comprenant lesdites 4-quinolinones et sur l'application pharmaceutique de celles-ci pour des maladies liées à des troubles leucocytaires, telles que des maladies inflammatoires et auto-immunes, notamment les rhumatismes, ainsi que sur leur utilisation en tant qu'anticoagulant, anti-venin, analgésique et anti-thrombotique.
Baraldi Patricia Tambarussi
Correa Arlene Goncalves
Soares Andreimar Martins
Fundacao Universidade Federal de Sao Carlos
Gowling Lafleur Henderson Llp
Universidade de Sao Paulo
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