Antisense modulation of x-linked inhibitor of apoptosis...

Details Antisense modulation of x-linked inhibitor of apoptosis... Antisense modulation of x-linked inhibitor of apoptosis...

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 48/00 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/11 (2006.01) C12N 15/15 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2384456

Antisense compounds, compositions and methods are provided for modulating the expression of X-linked inhibitor of apoptosis. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding X-linked inhibitor of apoptosis. Methods of using these compounds for modulation of X-linked inhibitor of apoptosis expression and for treatment of diseases associated with expression of X-linked inhibitor of apoptosis are provided.

La présente invention concerne des composés antisens, des compositions et des procédés pour la modulation de l'expression de l'inhibiteur réticulé d'apoptose. Les compositions comprennent des composés antisens, en particulier des oligonucléotides antisens, ciblés sur des acides nucléiques codant l'inhibiteur réticulé d'apoptose. La présente invention concerne également des procédés d'utilisation de ces composés pour la modulation de l'expression de l'inhibiteur réticulé d'apoptose et pour le traitement de maladies associées à l'expression de l'inhibiteur réticulé d'apoptose.

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