Benzisothiazole-1, 1-dioxide acting as antagonists to the...

Details Benzisothiazole-1, 1-dioxide acting as antagonists to the... Benzisothiazole-1, 1-dioxide acting as antagonists to the...

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/425 (2006.01)

Patent

CA 2591069

Compounds having formula (I) or a pharmaceutically acceptable salt, prodrug, or salt of a prodrug thereof, wherein L, A, G, R1, R2 and R3 are as defined herein. These compounds are particularly useful in the treatment of pain, inflammatory hyperalgesia, and urinary dysfunctions, such as bladder overactivity and urinary incontinence.

La présente invention décrit des composés de formule (I) ou leurs sels de qualité pharmaceutique, leurs prodrogues, ou un sel de l'une desdites prodrogues, où L, A, G, R1, R2 et R3 sont tels que définis dans la présente invention. Lesdits composés sont plus particulièrement utiles dans le traitement de la douleur, de l'hyperalgésie inflammatoire, et des dysfonctionnements urinaires, tels que l'hyperactivité vésicale et l'incontinence urinaire.

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