Late gestation lung genes, fragments and uses thereof

Details Late gestation lung genes, fragments and uses thereof Late gestation lung genes, fragments and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/15 (2006.01) A61K 31/7088 (2006.01) A61K 35/42 (2006.01) A61K 38/17 (2006.01) A61K 38/55 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) C07K 14/81 (2006.01) C07K 16/38 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2459728

The present invention provides a family of genes related to late gestation lung genes and fragments thereof. Embodiments of the present invention provide compositions and methods for the therapeutic treatment of disorders in the lung or other tissues. More particularly the invention provides methods for the treatmemt of abnormalities in alveolarization, and abnormalities in branching morphogenesis. In other embodiments of the invention the use of the LGL1 gene or related products or fragments thereof in research and diagnostics is provided.

La présente invention concerne une famille de gènes liés aux gènes du poumon à gestation tardive et à leurs fragments. Les modes de réalisation de la présente invention concernent des compositions et des procédés destinés au traitement thérapeutique des troubles dans les poumons ou d'autres tissus. L'invention concerne plus particulièrement des procédés de traitement des anomalies d'alvéolarisation et des anomalies de morphogenèse par ramification. Dans d'autres modes de réalisation de l'invention, l'invention concerne l'utilisation du gène LGL1 ou des produits correspondants ou de leurs fragments à des fins de recherche et de diagnostic.

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