Blood-compatible and bacteria-repellent copolymer

C - Chemistry – Metallurgy – 08 – F

Patent

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Details

C08F 228/02 (2006.01) A61L 27/34 (2006.01) A61L 29/00 (2006.01) A61L 29/08 (2006.01) A61L 31/00 (2006.01) A61L 31/10 (2006.01) A61L 33/00 (2006.01) C08F 220/04 (2006.01) C08F 222/02 (2006.01) C08G 18/08 (2006.01) C08G 18/62 (2006.01) C08J 3/28 (2006.01) C08J 7/04 (2006.01) C08J 7/12 (2006.01)

Patent

CA 2241374

Disclosed is a copolymer having units of (a) at least one monomer containing a sulfonic acid or sulfonate group, (b) at least one monomer containing a carboxyl or carboxylate group and (c) at least one monomer containing an NCO-reactive group. The copolymer may have up to 70 mol%, based on the total of monomers (a), (b) and (c) of units of one or more other monomers having either a different functionality to that of the monomers mentioned or no functionality. The copolymer can be covalently bonded to a hydrophilic surface of a polymer substrate by reaction with a polyisocyanate. Also disclosed is an article having a surface modified in this way useful for medical, hygiene, industrial, foodstuffs or bioengineering purposes.

Divulgation d'un copolymère comportant les motifs suivants : a) au moins un monomère possédant un groupement acide sulfonique ou sulfonate, b) au moins un monomère possédant un groupement carboxyle ou carboxylate et c) au moins un monomère possédant un groupement réactif NCO-. Ce copolymère peut contenir jusqu'à 70 %, relativement au nombre total de motifs a), b) et c), d'un ou plusieurs monomères possédant une fonctionnalité différente de celles des monomères susmentionnés ou ne possédant aucune fonctionnalité. Le copolymère peut être lié par covalence à la surface hydrophile d'un support polymère grâce à une réaction avec un polyisocyanate. On divulgue aussi un objet ayant une surface modifiée de cette manière, pouvant avoir des applications médicales, hygiéniques, industrielles, alimentaires ou biotechniques.

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