Quinazolinylmethylenethiazolinones as cdk1 inhibitors

Details Quinazolinylmethylenethiazolinones as cdk1 inhibitors Quinazolinylmethylenethiazolinones as cdk1 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 417/06 (2006.01) A61K 31/427 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2583311

The present invention discloses Quinazoline thiazolinone derivatives of the formula (I), wherein R1, R3, R4, X and n have the meanings as defined herein before, which demonstrate CDK1 antiproliferative activity and are useful as anti-cancer agents.

La présente invention a trait à des dérivés de quinazoline thiazolinone de formule (I), dans laquelle R1, R3, R4, X et n sont tels que définis dans la description, présentant une activité antiproliférante de CDK1 et utiles comme agents anticancéreux

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