Monoterpenoid derivatives for treatment of cancer

Details Monoterpenoid derivatives for treatment of cancer Monoterpenoid derivatives for treatment of cancer

A - Human Necessities

61

K

A61K 31/075 (2006.01) A61K 31/00 (2006.01) A61K 31/215 (2006.01) A61K 31/22 (2006.01)

Patent

CA 2322165

A method of inhibiting or preventing the growth of tumor cells is disclosed. In one embodiment, this method comprises the step of administering a compound selected from the group consisting of citracetal, citral dimethyl acetal, citral diethyl acetal, geranyl benzoate, geranyl tiglate, geranyl anthranilate, farnesyl benzoate, farnesyl anthranilate, farnesyl tiglate, farnesyl acetate and combinations there of to a human tumor patient, wherein the amount is effective to reduce or inhibit tumor growth by at least 50 %.

Cette invention a trait à une méthode visant à bloquer ou à empêcher la croissance de cellules tumorales. Dans un mode de réalisation, cette méthode consiste à administrer à un patient humain atteint de tumeur un composé issu du groupe constitué par du citracétal, du citral diméthyl acétal, du citral diéthyl acétal, du géranyl benzoate, du géranyl tiglate, du géranyl anthranilate, du farnésyl benzoate, du farnésyl anthranilate, du farnésyl tiglate, du farnésyl acétate et par leurs combinaisons, la quantité administrée étant propre à bloquer la croissance de la tumeur ou à la réduire d'au moins 50 %.

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