Methods and compositions for cell activation

Details Methods and compositions for cell activation Methods and compositions for cell activation

A - Human Necessities

61

K

A61K 48/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2576055

Methods and compositions for activating a cell are provided. In practicing the subject methods, a cell including a coding sequence for either a telomerase reverse transcriptase (TERT) or a telomerase RNA component (TERC) is activated by conditionally increasing expression of the coding sequence. Also provided are transgenic animals and systems for practicing the subject methods.

Cette invention concerne des procédés et des compositions d'activation de cellules. Lors de la réalisation de ces procédés, une cellule contenant une séquence de codage soit pour une transcriptase inverse de télomérase (TERT) soit un composant ARN de télomérase (TERC) est activée par augmentation conditionnelle de l'expression de la séquence de codage. Cette invention concerne également des animaux transgéniques et des systèmes de réalisation de ces procédés.

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