Pharmaceutical compounds

Details Pharmaceutical compounds Pharmaceutical compounds

C - Chemistry, Metallurgy

07

D

C07D 487/08 (2006.01) A61K 31/551 (2006.01) C07D 471/08 (2006.01) C12Q 1/04 (2006.01)

Patent

CA 2674011

Nonane and decane diazabicyclic derivatives having homopiperazine as main ring, having affinity for the opioidergic µ and/or .delta. and/or k receptors and/or for all their receptorial subclasses, with central and/or peripheral activity, having formula (I), the isomeric forms and their mixtures included, wherein one or more atoms are in the corresponding isotopic forms: (see formula I) wherein: - n is an integer equal to 1 or 2; - one of the substituents R and R1 of the nitrogen atoms of the di-- azabicyclic ring is a -C(O)-R B group, wherein R B is a C1-C10 alkyl group, linear or branched when possible, - the other remained substituent of R and R1 has the meanings re--ported in the description.

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