C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/01 (2006.01) A61K 35/76 (2006.01) A61K 38/21 (2006.01) A61K 39/42 (2006.01) A61P 35/00 (2006.01) C12N 7/00 (2006.01) C12N 7/02 (2006.01)
Patent
CA 2305269
The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
L'invention concerne des virus qui peuvent se répliquer, et par conséquent, tuer les cellules néoplasiques présentant une déficience de la réponse antivirale induite par interféron. L'invention traite également de l'utilisation de ces virus pour traiter les maladies néoplasiques y compris le cancer et les tumeurs importantes. Les virus de l'ARN et de l'ADN sont utiles à cet égard. L'invention concerne également des procédés permettant de sélectionner, concevoir, purifier et utiliser lesdits virus pour soigner le cancer.
Groene William S.
Lorence Robert M.
Rabin Harvey
Roberts Michael S.
von Borstel Reid W.
Gowling Lafleur Henderson Llp
Pro-Virus Inc.
Wellstat Biologics Corporation
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