Stable emulsion suitable for pharmaceutical administration,...

Details Stable emulsion suitable for pharmaceutical administration,... Stable emulsion suitable for pharmaceutical administration,...

A - Human Necessities

61

K

A61K 9/107 (2006.01) A61K 31/275 (2006.01) A61K 31/54 (2006.01)

Patent

CA 2041920

Abstract of the Disclosure: A stable active substance emulsion of the oil-in-water type with a phospholipid as emulsifier is described, where the active substance dissolved in the lipid phase has one or more basic groups, is hydrophobic and oil-soluble, and has a pKa of at least 7.5, the aqueous phase is set at an acid pH, and the disperse phase gives a positive zeta potential of at least +15, but preferably +30, mV after dilution of the emulsion ready for administration to a fat content of 0.08 % by weight.

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