Method for treating or preventing a pancreatic dysfunction

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/077 (2010.01) A61K 35/12 (2006.01) A61K 35/39 (2006.01) A61P 1/18 (2006.01) A61P 5/48 (2006.01) C12N 5/02 (2006.01)

Patent

CA 2744228

The present invention provides a method for improving pancreatic function in a subject in need thereof, the method comprising administering to the subject STRO-1+ cells and / or progeny cells thereof and / or soluble factors derived therefrom. The method of the invention is useful for treating and / or preventing and / or delaying the onset or progression of a disorder resulting from or associated with pancreatic dysfunction, e.g., resulting from abnormal endocrine or exocrine function of the pancreas.

La présente invention concerne un procédé pour améliorer la fonction pancréatique chez un sujet nécessitant ceci, le procédé comprenant ladministration au sujet de cellules STRO-1+ et/ou de cellules descendantes de celles-ci et / ou de facteurs solubles dérivés de celles-ci. Le procédé de linvention est utile pour traiter et/ou prévenir et/ou retarder lapparition ou la progression dun trouble résultant de, ou associé à un dysfonctionnement pancréatique, par exemple, résultant dune fonction endocrine ou exocrine anormale du pancréas.

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