Composition for the prevention and/or treatment of the...

A - Human Necessities – 61 – K

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A61K 31/221 (2006.01) A61K 31/198 (2006.01) A61P 39/00 (2006.01)

Patent

CA 2400728

A composition is disclosed which is suitable for the prevention and/or treatment of cell and tissue abnormalities of exogenous, toxic or metabolic origin and suitable for reducing the toxic effects of cyclosporin-A and other immunosuppressive agents, which may take the form of a food supplement or of an actual medicine, containing as its active ingredients in combination or separately packaged: (a) propionyl L-carnitine or one of its pharmacologically acceptable salts, and (b) an amino acid selected from the group consisting of glycine, serine, alanine and arginine, or mixtures thereof.

L'invention concerne une composition convenant pour la prévention et/ou le traitement d'anomalies des cellules et des tissus d'origine exogène, toxique ou métabolique, indiquée pour la réduction des effets toxiques de la cyclosporine A et d'autres agents immunosuppresseurs. Cette composition peut se présenter sous forme de supplément nutritif ou de médicament contenant comme agents actifs : (a) la L-carnitine de propionyl ou un de ses sels pharmaceutiquement acceptables, et (b) un acide aminé sélectionné dans le groupe constitué de la glycine, la sérine, l'alanine l'arginine ou leurs mélanges, conditionnés conjointement ou séparément.

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