Method of replicating viruses in suspension cultures of dog...

C - Chemistry – Metallurgy – 12 – N

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C12N 7/00 (2006.01)

Patent

CA 2726513

Animal cells are described which can be infected by viruses and which are adapted to growth in suspension in medium free of animal-derived components, such as serum-free medium. Processes for the replication of viruses in cell culture using these cells are furthermore described, as well as vaccines which contain the viruses or antigenic portions thereof obtainable by the process.

L'invention porte sur des cellules animales qui peuvent être infectées par des virus et qui sont aptes à la croissance en suspension dans un milieu exempt de composants d'origine animale, tel que du milieu sans sérum. L'invention porte en outre sur des procédés pour la réplication de virus dans une culture cellulaire utilisant ces cellules, ainsi que sur des vaccins qui contiennent les virus ou des parties antigéniques de ceux-ci pouvant être obtenus par le procédé.

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