Germicidal antiseptic composition for dilution

A - Human Necessities – 61 – K

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Details

A61K 31/155 (2006.01) A01N 25/02 (2006.01) A01N 25/22 (2006.01) A01N 25/30 (2006.01) A01N 47/44 (2006.01) A61L 2/18 (2006.01) A61P 31/02 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2523207

A dilution-type sterilizer composition which has excellent formulation stability and does not generate an insoluble sediment even when diluted with inorganic-ion-containing water such as tap water at time of use. The composition hence retains excellent sterilizing ability. The dilution-type sterilizer composition is a water-based liquid formulation containing chlorhexidine gluconate as a major ingredient and is characterized by comprising (1) 1 to 10 w/v% chlorhexidine gluconate, (2) 1 to 10 w/v% one or more members selected among polyoxyethylene alkyl ethers and polyoxyethylene alkenyl ethers which have an HLB of 10 to 15 and a solidifying point of 35~C or lower, (3) 0.001 to 0.5 w/v% water-soluble organic C2-6 monocarboxylic acid, and (4) water.

La présente invention concerne une composition de stérilisation de type à dilution dont la formulation a une excellente stabilité et qui ne produit pas de sédiments insolubles même lorsqu'elle est diluée avec de l'eau contenant des ions minéraux telle que de l'eau du robinet en cours d'utilisation. La composition conserve ainsi une excellente capacité de stérilisation. La composition de stérilisation de type à dilution est une formulation liquide à base d'eau contenant du gluconate de chlorhexidine comme composante principale, et se caractérise en ce qu'elle comprend (1) 1 à 10 % poids/vol. de gluconate de chlorhexidine, (2) 1 à 10 % poids/vol. d'un ou de plusieurs éléments choisis parmi les polyoxyéthylène alkyl éthers et les polyoxyéthylène alcényl éthers qui ont un HLB de 10 à 15 et une température de solidification de 35 ·C ou moins, (3) 0,001 à 0,5 % poids/vol. d'un acide monocarboxylique en C¿2-6? organique soluble dans l'eau, et (4) de l'eau.

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