Substituted 3-aminosydnone imines, processes for their...

Details Substituted 3-aminosydnone imines, processes for their... Substituted 3-aminosydnone imines, processes for their...

C - Chemistry, Metallurgy

07

D

167/212, 260/243

C07D 417/04 (2006.01) A61K 31/54 (2006.01) C07D 271/04 (2006.01)

Patent

CA 2019811

ABSTRACT Substituted 3-aminosydnone imines of the formula I Image (I) and their pharmacologically acceptable acid addition salts, in which A denotes the radical -S- or -SO2-, R1 denotes the radical -CO-R2 or hydrogen, and R2 denotes, for example, (C1 to C4)alkyl, are prepared by cyclization of a compound of the formula II Image (II) and, if desired, subsequent acylation. The compounds have haemodynamic, thrombocyte function inhibiting an antithrombotic properties and are useful in the combating and prevention of cardiovascular disorders.

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