Focused libraries of genetic packages

Details Focused libraries of genetic packages Focused libraries of genetic packages

C - Chemistry, Metallurgy

40

B

C40B 40/08 (2006.01) C12N 15/10 (2006.01) C12N 15/13 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2432377

Focused libraries of vectors or genetic packages that display, display and express, or comprise a member of a diverse family of antibody peptides, polypeptides or proteins and collectively display, display and express, or comprise at least a portion of the focused diversity of the family. The libraries have length and sequence diversities that mimic that found in native human antibodies.

L'invention concerne des banques ciblées de vecteurs ou de capsides génétiques qui affichent, affichent et expriment, ou comprennent un membre d'une famille diverse de peptides, polypeptides ou protéines d'anticorps et affichent, affichent et expriment, ou comprennent, de manière collective, au moins une partie de la diversité ciblée de ladite famille. Ces banques présentent des diversités de longueur et de séquence qui imitent celles trouvées dans des anticorps humains natifs.

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