Modulators of metabolism and the treatment of disorders...

Details Modulators of metabolism and the treatment of disorders... Modulators of metabolism and the treatment of disorders...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/506 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2656520

The present invention relates to 4-[6-(6-methanesulfonyl-2-methyl-pyridin-3-ylamino)-5-methyl-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester, pharmaceutically acceptable salts, solvates and hydrates thereof that are modulators of glucose metabolism. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and complications thereof, such as, diabetes and obesity.

La présente invention concerne le 4-[6-(6-méthanesulfonyl-2-méthyl-pyridin-3-ylamino)-5-méthyl-pyrimidin-4-yloxy]-pipéridine-1-carboxylate d'isopropyle, et ses sels, solvates et hydrates de qualité pharmaceutique, ces composés étant des modulateurs du métabolisme du glucose. Ainsi, les composés selon la présente invention peuvent être employés dans le traitement de troubles de type métabolique et de leurs complications, par exemple le diabète et l'obésité.

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