A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/554 (2006.01) A61K 31/165 (2006.01) A61K 31/421 (2006.01) A61K 31/4245 (2006.01) A61K 31/433 (2006.01) A61K 31/4355 (2006.01) A61K 31/437 (2006.01) A61P 33/06 (2006.01)
Patent
CA 2731224
Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a human, comprising administering an effective amount of an inhibitor or a combina-tion of inhibitors. An example of such an inhibitor is a compound of formula I, Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein.
L'invention porte sur des inhibiteurs du canal anionique de surface de plasmodium (PSAC) et sur leur utilisation dans le traitement ou la prévention du paludisme dans un animal tel qu'un être humain, comprenant l'administration d'une quantité efficace d'un inhibiteur ou d'une combinaison d'inhibiteurs. Un exemple d'un tel inhibiteur est un composé de formule I, Formule 1 (I) ou un sel pharmaceutiquement acceptable de celui-ci, dans laquelle R1 à R7 sont tels que décrits dans la description.
Desai Sanjay A.
Pillai Ajay D.
Departmen T. Of Health And Human Services The United States Of America As Represented By The Secretary
Ridout & Maybee Llp
LandOfFree
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