Time-resolved fluorescence assay for the detection of...

A - Human Necessities – 61 – K

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A61K 31/425 (2006.01) A61K 31/365 (2006.01) A61K 31/395 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01) G01N 33/566 (2006.01) G01N 33/60 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2477985

The present invention provides for a polypeptide aggregation screening assay for the purpose of detecting modulators of polypeptide aggregation, which can provide for new therapies in pathologic states associated with polypeptide aggregation, especially considered is Alzheimer~s disease.

L'invention concerne un essai de criblage pour l'agrégation de polypeptides dans le but de détecter des modulateurs d'agrégation de polypeptides. Cet essai peut permettre d'obtenir de nouvelles thérapies pour des états pathologiques associés à l'agrégation de polypeptides, et plus spécialement pour la maladie d'Alzheimer.

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