Methods and compositions for treating gastrointestinal...

A - Human Necessities – 61 – K

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A61K 31/559 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2690273

Methods are provided directed to administering a therapeutically effective amount of a prostaglandin EP4 agonist component to a mammal afflicted with or prone to affliction with a disease or condition selected from an esophageal ulcer, alcohol gastropathy, a duodenal ulcer, a gastric ulcer, non-steroidal anti- inflammatory drug-induced gastroenteropathy and intestinal ischemia. Such administration results in treating or preventing the disease or condition.

L'invention concerne des procédés destinés à l'administration d'une quantité thérapeutiquement efficace d'un composant agoniste de prostaglandine EP4 à un mammifère atteint ou prédisposé à une maladie ou une affection choisie parmi un ulcère de l'sophage, une gastropathie liée à l'alcool, un ulcère du duodénum, un ulcère gastrique, une gastro-entéropathie induite par un médicament anti-inflammatoire non stéroïdien et une ischémie intestinale. Une telle administration conduit à un traitement ou à une prévention de la maladie ou de l'affection.

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