Piperazine derivatives as 5-ht1b antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/10 (2006.01) A61P 25/24 (2006.01) C07D 209/08 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 403/10 (2006.01) C07D 413/10 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2385737

Piperazine derivatives of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in therapy as 5- HT1B antagonists. W,Y,Ra-Reare so defined in the application.

L'invention concerne des dérivés de pipérazine représentés par la formule (I), des procédés permettant de préparer ces dérivés, des compositions pharmaceutiques contenant ces dérivés et l'utilisation de ces dérivés en tant qu'antagonistes de 5-HT¿1B?. W, Y, R?a¿-R?e¿ sont tels que définis dans le descriptif.

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