Novel 2,3 disubstituted-(5,6)-heteroarylfused-pyrimidine-4-ones

Details Novel 2,3 disubstituted-(5,6)-heteroarylfused-pyrimidine-4-ones Novel 2,3 disubstituted-(5,6)-heteroarylfused-pyrimidine-4-ones

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/505 (2006.01) A61K 31/519 (2006.01) C07D 471/04 (2006.01) C07D 475/02 (2006.01) C07D 487/04 (2006.01) C07D 491/048 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2205274

The present invention relates to novel compounds of the formula I (see formula I) (preferred values are as follows: fused heterocyclic ring A is (see formula II) or (see formula III) is phenyl substituted at the 2 position with fluoro, bromo, chloro, methyl or trifluoro- methyl, R2 is phenyl substituted at the 2 position with fluoro, chloro, hydroxy or cyano, and the dashed line is a double bond), and their pharmaceutically acceptable salts, and pharmaceutical compositions and methods of treating neurode- generative and CNS-trauma related conditions.

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