Mammalian alpha-helical protein - 12

Details Mammalian alpha-helical protein - 12 Mammalian alpha-helical protein - 12

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) A61P 43/00 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C07K 16/42 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2360584

The present invention relates to polynucleotide and polypeptide molecules for mammalian alpha helix-12 (Zalpha12). The polypeptides, and polynucleotides encoding them, are hormonal and may be used to regulate the functioning of the immune system. The present invention also includes antibodies to the Zalpha12 polypeptides. Antagonists may be used to treat inflammation and inflammation- related diseases.

La présente invention concerne des molécules polynucléotidiques et polypeptidiques de la protéine-12 mammalienne à hélice alpha (Zalpha-12). Les polypeptides et les polynucléotides codant ces polypeptides sont hormonaux et peuvent être utilisés pour réguler le fonctionnement du système immunitaire. L'invention concerne en outre des anticorps anti-polypeptides Zalpha-12. Des antagonistes sont utilisés pour traiter des inflammations et des maladies apparentées à des inflammations.

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