Mammalian adhesion protease peptides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/64 (2006.01) A61K 38/43 (2006.01) C07K 14/705 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2381945

The present invention relates to polynucleotide and polypeptide molecules, and variants thereof, for MAPP, a novel member of the Disintegrin Proteases. The polypeptides, and polynucleotides encoding them, are cell-cell interaction modulating and may be used for delivery and therapeutics. The present invention also includes antibodies to the MAPP polypeptides.

La présente invention concerne des molécules polynucléotides et polypeptides, et des variantes de celles-ci, destinées à des MAPP, un nouveau membre des disintégrines protéases. Les polypeptides et les polynucléotides codant ces disintégrines protéases exercent un effet modulateur sur l'interaction intercellulaire et peuvent être mis en application sur le plan médical et thérapeutique. La présente invention concerne également des anticorps de polypeptides de MAPP.

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